Author

Li Yuan

Chinese Academy of Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:contrastive learning· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Can HuiD· 1 shared Cheng ChangiD· 1 shared Fan YangiD· 1 shared Guangyue Li· 1 shared Jianhua YaoiD· 1 shared Jingjie ZhangiD· 1 shared Jun Zhu· 1 shared Kaikun XuiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Can HuORCID

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2 papers

Recent·Most cited

Droplet-based organoid screens enable high-throughput identification of cancer vulnerabilities

Yanan Xia, Yuting Sun, Yimin Wang, Mingyang Zhang, Guangyue Li, Xinyi Dai, Xinyue Li, Can Hu, Zhiyuan Xu, Li Yuan, Zhiguo Zheng, Xiangdong Cheng, Xin Jin

This paper introduces a droplet-based organoid culture method for high-throughput screening of cancer vulnerabilities, identifying novel therapeutic targets in stomach cancer.

bioRxiv · Oct 19, 2026 · PreprintCancer Biology

MolSpecFlow: Mass-Constrained Hybrid Flow Matching for Joint Molecular-Spectral Analysis

Yu Wang, Fan Yang, Kaikun Xu, Li Yuan, Jun Zhu, Jingjie Zhang, Zhenchao Tang, Yatao Bian, Cheng Chang, Yonghong Tian, Jianhua Yao

MolSpecFlow bridges the gap between molecules and mass spectra using a hybrid flow matching model, achieving state-of-the-art results in de novo generation and spectral simulation.

bioRxiv · Feb 1, 2026 · PreprintBioinformatics