Liam McCarthy

Adaptation to warm environments with a fast pace of life in a marine predatory snail

This study examines local adaptation in marine snails to temperature regimes, finding that low latitude populations exhibit faster growth and early reproduction, while high latitude populations grow slower but reach larger sizes later.

Ddp1 cooperates with Ppx1 to counter a stress response initiated by non-vacuolar polyphosphate

The paper investigates how Ddp1 and Ppx1 counter polyphosphate toxicity in yeast by analyzing stress responses and enzyme functions.

A broad response to intracellular long-chain polyphosphate in human cells

This study shows that internally produced polyP in human cells activates signaling pathways and alters gene and protein expression through ectopic expression of a bacterial polyP synthetase.

Proteins required for vacuolar function are targets of lysine polyphosphorylation in yeast

The paper identifies 8 new polyphosphorylated proteins in yeast, including vacuolar proteins, and suggests a feedback regulation model for polyP synthesis.