Author

Lianna D’Brant

Neural Stem Cell Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

David C. Butler· 2 shared Michael J. MilleriD· 2 shared Natasha Rugenstein· 2 shared Timothy F. CzajkaiD· 2 shared Adam Tully WaickmaniD· 1 shared Ava R. JarvisiD· 1 shared Celeste M M. KarchiD· 1 shared Céline HardyiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersMicrobiology

David C. Butler

Mutual co-authors in cluster

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2 papers

Recent·Most cited

MicrobiologyBrain PathologyPeer-reviewedMar 26, 2025

HSV-1 Infection Alters MAPT Splicing and Promotes Tau Pathology in Neural Models of Alzheimer's Disease

Emmanuel C. Ijezie, Michael J. Miller, Céline Hardy…·David C. Butler

This study shows HSV-1 infection alters MAPT splicing, increases 4R-Tau protein and hyperphosphorylation, and promotes Tau pathology in neural models.

17 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintMay 28, 2024

Fully Human Bifunctional Intrabodies Achieve Graded Reduction of Intracellular Tau and Rescue Survival of MAPT Mutation iPSC-derived Neurons

Lianna D’Brant, Natasha Rugenstein, Su Kyoung Na…·David C. Butler

The paper develops fully human bifunctional anti-tau intrabodies that reduce intracellular tau and improve neuronal survival in disease-associated mutations.

8 citations

humanproteomics

𝕏 PostBluesky