Potentiation of cerebellar Purkinje cells facilitates whisker reflex adaptation through increased simple spike activity
Vincenzo Romano, Licia De Propris, Laurens W. J. Bosman, Pascal Warnaar, Michiel M. ten Brinke, Sander Lindeman, Chiheng Ju, Arthiha Velauthapillai, Jochen K. Spanke, Emily Middendorp Guerra, Tycho M. Hoogland, Mario Negrello, Egidio Ugo D'Angelo, Chris I. De Zeeuw
This study shows that increased simple spike activity in Purkinje cells, facilitated by long-term potentiation at parallel fiber synapses, contributes to whisker reflex adaptation in mice.
eLife · Dec 18, 2018Peer-reviewedNeuroscience