Author

Lidvine Genet

Ludwig Cancer Research

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Molecular Biology· 1

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Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Céline Mouton· 1 shared Christian Pecquet· 1 shared Emilie LeroyiD· 1 shared Gabriel LevyiD· 1 shared Ian C. Brett· 1 shared Jean‐Philippe DefouriD· 1 shared Judith StaerkiD· 1 shared Nicolas PapadopoulosiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Céline Mouton

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1 paper

Recent·Most cited

Constitutive Activation and Oncogenicity Are Mediated by Loss of Helical Structure at the Cytosolic Boundary of the Thrombopoietin Receptor

Jean‐Philippe Defour, Emilie Leroy, Sharmila Dass, Thomas Balligand, Gabriel Levy, Ian C. Brett, Nicolas Papadopoulos, Céline Mouton, Lidvine Genet, Christian Pecquet, Judith Staerk, Steven O. Smith, Stefan N. Constantinescu

The paper investigates how mutations in the thrombopoietin receptor (TpoR) affect its activation and oncogenicity by altering the helical structure at the cytosolic boundary of the transmembrane domain.

eLife · Jun 20, 2023Peer-reviewedMolecular Biology