Author

Judith Staerk

Ludwig Cancer ResearchORCID 0000-0001-8698-6998Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Artur Cieslar-Pobuda· 1 shared Bernhard SchmiereriD· 1 shared Céline Mouton· 1 shared Christian Pecquet· 1 shared Diana L. Bordin· 1 shared Eero Tölö· 1 shared Eivind ValeniD· 1 shared Emilie LeroyiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Artur Cieslar-Pobuda

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2 papers

Recent·Most cited

Molecular BiologyeLifePeer-reviewedJun 20, 2023

Constitutive Activation and Oncogenicity Are Mediated by Loss of Helical Structure at the Cytosolic Boundary of the Thrombopoietin Receptor

Jean‐Philippe Defour, Emilie Leroy, Sharmila Dass…·Stefan N. Constantinescu

The paper investigates how mutations in the thrombopoietin receptor (TpoR) affect its activation and oncogenicity by altering the helical structure at the cytosolic boundary of the transmembrane domain.

10 citations

humanexperimental assay

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Molecular BiologyeLifePeer-reviewedDec 13, 2021

Rapid genome editing by CRISPR-Cas9-POLD3 fusion

Ganna Reint, Zhuokun Li, Kornel Labun…·Emma Haapaniemi

The paper evaluates DNA repair protein-Cas9 fusions for improving CRISPR editing efficiency, finding that most require optimization for specific cell types and genomic loci.

20 citations

CRISPR screenexperimental assay

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