Author
Ludwig Cancer ResearchORCID 0000-0002-8599-2699Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Jean‐Philippe Defour, Emilie Leroy, Sharmila Dass…·Stefan N. Constantinescu
The paper investigates how mutations in the thrombopoietin receptor (TpoR) affect its activation and oncogenicity by altering the helical structure at the cytosolic boundary of the transmembrane domain.
Núria Suelves, Shirine Saleki, Tasha Ibrahim…·Pascal Kienlen‐Campard
Daniela Matuozzo, Estelle Talouarn, Astrid Marchal…·Michel Vidaud
The paper identifies rare loss-of-function variants in type I IFN immunity genes associated with severe COVID-19, particularly in younger patients with recessive inheritance.
Florian Perrin, Nicolas Papadopoulos, Núria Suelves…·Stefan N. Constantinescu
The paper shows that dimeric orientations of C99 influence γ-secretase cleavage lines, affecting Aβ42 processing and gene transcription.