Aging restricts maturation of CXCL13+ T follicular helper cells in human immunity
Nathan A. Bracey, Casey Beppler, Tatjana Bilich, Adrienne H. Long, Elsa Solà, Aviv Barak, Timothy J Few-Cooper, Azam Mohsin, Vishnu Shankar, Vamsee V. A. Mallajosyula, Lilit Kamalyan, Robson Capasso, Shai S. Shen-Orr, Mark M. Davis
This study identifies age-related defects in CXCL13+ T follicular helper cells in human tonsil organoids, linking them to reduced antibody responses.
Cell Reports · Jun 1, 2026Peer-reviewedImmunology