Prasanna Jagannathan

The paper examines how exposure to P. falciparum and common cold viruses influences vaccine responses in Ugandan infants, finding positive associations between microbial exposure and antibody levels.

The paper characterizes malaria-specific Tfh and Tr1 cells in a longitudinal cohort, finding overlapping phenotypes and showing their decline after transmission interruption.

The paper identifies CXCR6⁺ CD127⁻ Tr1 cells as key regulators in Plasmodium falciparum infection, showing they balance immunity and parasite persistence.

This study investigates B cell and antibody responses to PfARMA, finding that IgM and IgG predominantly target the N-terminal IDR1 region, but these responses do not correlate with protection against malaria.

This study shows that malaria exposure increases cytotoxic Vδ2+ T cell expansion in human tonsil and spleen organoids, with clonal expansion and activation, while not significantly affecting influenza vaccine responses.

The paper examines how maternal malaria and early-life infections affect P. falciparum-specific antibody responses in infants, finding no protective association between maternal antibodies or early infections and clinical malaria.

The paper examines inhibitory NK receptors on γδ T cells in Ugandan children, finding that some enhance and others reduce antimalarial responses to repeated infections.

This study identifies sex-specific immune correlates of Long COVID development, persistence, and resolution using multi-omic analyses of blood samples from patients with and without Long COVID.