Author

Lina Igel

Helios Klinikum Krefeld

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Assay:bulk RNA-seq· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Adam Desrochers· 1 shared Antonia Eicher· 1 shared Arek KendirliiD· 1 shared Baerbel KelleriD· 1 shared Catharina SchütziD· 1 shared Christine WolfiD· 1 shared Hagen Ott· 1 shared Jasmin Beate Kümmerle-Deschner· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam Desrochers

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1 paper

Recent·Most cited

Truncating RELA variants drive autoinflammation and autoimmunity by impairing the negative feedback control of NF-kB

Nadja Lucas, Sophia Weidler, Antonia Eicher, Baerbel Keller, Özlem Şatırer, Adam Desrochers, Timothy J.S. Ramnarine, Mohammad Mokhtari, Sophie Elstner, Timmy Strauß, Simon Mages, Arek Kendirli, Oana Buzoianu, Lina Igel, Tim Niehues, , Min Ae Lee‐Kirsch

This study identifies truncating RELA variants causing autoinflammation and autoimmunity by disrupting NF-κB feedback control and immune homeostasis.

bioRxiv · Nov 9, 2025 · PreprintImmunology