Author

Linda N. Tran

University of Washington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 2

Signature Assays, Organisms & Methods

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Assay:CRISPR screen· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:variant calling· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Alexander M. LoibeniD· 2 shared Ashley MckinstryiD· 2 shared Charles E. MurryiD· 2 shared Clayton E. FriedmaniD· 2 shared Dania Ahmed· 2 shared Douglas M. FowleriD· 2 shared Kai‐Chun YangiD· 2 shared Lea M. StaritaiD· 2 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenetics

Alexander M. LoibenORCID

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2 papers

Recent·Most cited

Multiplexed functional assessments of MYH7 variants in human cardiomyocytes at scale

Clayton E. Friedman, Shawn Fayer, Sriram Pendyala, Wei‐Ming Chien, Linda N. Tran, Leslie S. Chao, Ashley Mckinstry, Dania Ahmed, Alexander M. Loiben, Stephen D. Farris, April Stempien‐Otero, Erica C. Jonlin, Charles E. Murry, Lea M. Starita, Douglas M. Fowler, Kai‐Chun Yang

This study uses hiPSC-derived cardiomyocytes to assess MYH7 variants' effects, showing pathogenic variants reduce protein abundance and cell survival.

bioRxiv · Jul 28, 2023 · PreprintGenetics

CRaTER enrichment for on-target gene-editing enables generation of variant libraries in hiPSCs

Clayton E. Friedman, Shawn Fayer, Sriram Pendyala, Wei‐Ming Chien, Alexander M. Loiben, Linda N. Tran, Leslie S. Chao, Ashley Mckinstry, Dania Ahmed, Elaheh Karbassi, Aidan M. Fenix, Charles E. Murry, Lea M. Starita, Douglas M. Fowler, Kai‐Chun Yang

CRaTER enriches for on-target gene-edited cells in hiPSCs, enabling efficient generation of variant libraries for studying cardiomyopathy-associated mutations.

Journal of Molecular and Cellular Cardiology · Apr 3, 2023Peer-reviewedGenetics