Dissecting the homeodomain MAT locus and engineering novel tripolar and bipolar mating systems in Cryptococcus amylolentus
Liping Xiong, Vikas Yadav, Sheng Sun, Joseph Heitman
This study investigates the role of HD genes in sexual reproduction and demonstrates a tetrapolar-to-bipolar transition in Cryptococcus amylolentus using CRISPR-Cas9 gene editing.
mBio · Mar 17, 2026Peer-reviewedMicrobiology