Vikas Yadav

The paper identifies the protein phosphatase 2C domain of adenylyl cyclase in Cryptococcus neoformans as essential for its pathobiological functions, affecting virulence and immune response.

The paper discovers a new family of giant viruses, Mycodnaviridae, that infect zoosporic fungi and persistently infect them, expanding the known host range of Nucleocytoviricota.

This study identifies HXK1 and HXK2 as genetic suppressors of Tps1 loss-of-function in C. deneoformans, revealing their role in regulating glycolytic flux to restore thermotolerance.

This study investigates the role of HD genes in sexual reproduction and demonstrates a tetrapolar-to-bipolar transition in Cryptococcus amylolentus using CRISPR-Cas9 gene editing.

This paper identifies 4456dh, a small molecule inhibitor of trehalose-6-phosphate synthase, which disrupts fungal thermal tolerance and virulence.

This study identifies a thermoregulatory network in Cryptococcus neoformans that governs virulence through calcineurin signaling, using genetic, proteomic, and transcriptomic approaches.

This study identifies two mechanisms that bypass calcineurin function in Cryptococcus deneoformans during high-temperature growth, revealing its role in cytokinesis under thermal stress.

The paper identifies RNAi loss-of-function mutations in Cryptococcus neoformans and shows they can lead to hypermutation when combined with transposon burdens.

The paper shows calcineurin regulates RNAi-mediated transgene silencing and small RNA production in Cryptococcus neoformans through P-body localization and substrate interactions.

This study investigates epigenetic dynamics of centromeres and neocentromeres in Cryptococcus deuterogattii, showing neocentromeres are unstable and lack epigenetic memory.

This study shows that centromere scission in Cryptococcus neoformans leads to chromosome translocations, reproductive isolation, and speciation-like effects without altering gene sequences.

This study identifies unusual centromere dynamics and maps centromere DNA sequences in the rice blast fungus Magnaporthe oryzae, revealing epigenetic specification of centromere function.