Integrated kidney and urine proteomics define encrypted antimicrobial peptides as effectors of host defence in human pyelonephritis
Lars Borgards, Hannah Voß, Stephanie Tautges, Bente Siebels, Ekaterina Pylaeva, Philippa Spangenberg, Devon Siemes, Christoph Krisp, Jessica Schmitz, Lisa Cinkul, Damilola Emmanuel Akinyemi, Annika Hilger, Paulina Szymczak, Anne-Christine Aust, Jan Hinrich Braesen, , Olga Shevchuk
The paper integrates kidney and urine proteomics with peptidomics and machine learning to identify encrypted antimicrobial peptides as functional effectors in human pyelonephritis.
bioRxiv · Apr 14, 2026 · PreprintImmunology