Hannah Voß

Integrated kidney and urine proteomics define encrypted antimicrobial peptides as effectors of host defence in human pyelonephritis

The paper integrates kidney and urine proteomics with peptidomics and machine learning to identify encrypted antimicrobial peptides as functional effectors in human pyelonephritis.

Lactate-dependent metabolic rewiring is associated with CD163+ macrophage polarization in human pyelonephritis

This study identifies lactate as a metabolic driver of CD163+ macrophage polarization in human pyelonephritis, linking lactate metabolism to immune dysfunction.

TSP1/TGF-β1 drives arachidonic acid metabolism to orchestrate neutrophil swarming

The paper identifies TSP1/TGF-β1 as a key driver of neutrophil swarming through arachidonic acid metabolism in a urinary tract infection model.

Astrocytic PIEZO activation by heartbeat sound promotes extracellular matrix and maturation in human brain organoids

This study shows that heartbeat sound activates PIEZO channels in astrocytes, promoting extracellular matrix synthesis and neural differentiation in human brain organoids.

Efficient enzyme-free isolation of brain-derived extracellular vesicles

This paper demonstrates that non-enzymatic methods can isolate brain-derived extracellular vesicles without compromising protein integrity, achieving high yield and purity.

Cystatin C loaded in brain-derived extracellular vesicles rescues synapses after ischemic insult in vitro and in vivo

This study identifies cystatin C as a neuroprotective protein upregulated after stroke and shows that delivering it via brain-derived extracellular vesicles improves synaptic preservation in vitro and in vivo.