Fatty Acid Synthase associates with nuclear-derived cytoplasmic dsRNA molecules and influences antiviral innate immune response
Charline Pasquier, Mélanie Messmer, Lise Moroge, Lisanne I Knol, Johana Chicher, Richard Patryk Ngondo, Sébastien Pfeffer, Erika Girardi
This study shows FASN depletion increases cytoplasmic endogenous dsRNA and enhances antiviral innate immune responses.
bioRxiv · Jul 16, 2025 · PreprintImmunology