Author

Longchen Xu

Center for Life Sciences

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Approach:contrastive learning· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Ryō YamamotoiD· 2 shared Xun LaniD· 2 shared Hengyi XuiD· 1 shared Hiromitsu NakauchiiD· 1 shared Hiroshi HaenoiD· 1 shared Jianwei WangiD· 1 shared Jun Ooehara· 1 shared Keimyo Imamura· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCell Biology

Ryō YamamotoORCID

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2 papers

Recent·Most cited

Stable platelet production via the bypass pathway explains the long-term reconstitution capacity of hematopoietic stem cells

Shoya Iwanami, Toshiko Sato, Hiroshi Haeno, Longchen Xu, Keimyo Imamura, Jun Ooehara, Xun Lan, Hiromitsu Nakauchi, Shingo Iwami, Ryō Yamamoto

This study identifies a myeloid bypass pathway that supports long-term HSC reconstitution by analyzing single-cell transplantation data with a mathematical model.

iScience · Apr 29, 2025Peer-reviewedCell Biology

Dissecting cell state transitions by causal inference

Longchen Xu, Tingting Cong, Hengyi Xu, Naixue Yang, Tian Chen, Sijie Yang, Ming Zhu, Rahul Sinha, Ryō Yamamoto, Wei Zhang, Jianwei Wang, Xun Lan

CIBER is a causal inference framework for analyzing cell state transitions, identifying key features in differentiation processes and predicting novel regulatory associations.

bioRxiv · Feb 8, 2023 · PreprintSystems Biology