Powering methanogenesis from fatty acids by a twin-heme-mediated reverse redox-loop
Dennis Kosian, Lin Zhang, Lena Appel, Lorenz Heidinger, Friedel Drepper, Pitter F. Huesgen, Oliver Einsle, Matthias Boll
This paper reports cryo-EM structures of EMO and EMO-ETF complex from Syntrophus aciditrophicus, revealing a twin-heme-mediated reverse redox-loop mechanism for methanogenesis from fatty acids.
bioRxiv · Aug 21, 2026 · PreprintMicrobiology