Sox9-dependent plasticity of esophageal progenitors is fine-tuned by cues from the microenvironment
Louison Descampe, Benjamin Dassy, Fadi Charara, Ligia Craciun, Laurine Verset, Sheleya Pirard, Quentin Verheye, Morgane Leprovost, Marie‐Isabelle Garcia, Alizée Vercauteren Drubbel, Benjamin Beck
The paper shows that Sox9-dependent plasticity in esophageal progenitors is regulated by Hedgehog-induced TGF-β and BMP pathways, and can be modulated by Ibuprofen in vivo.
bioRxiv · Mar 21, 2025 · PreprintCell Biology