Marie‐Isabelle Garcia

Sox9-dependent plasticity of esophageal progenitors is fine-tuned by cues from the microenvironment

The paper shows that Sox9-dependent plasticity in esophageal progenitors is regulated by Hedgehog-induced TGF-β and BMP pathways, and can be modulated by Ibuprofen in vivo.

An Lgr5-independent developmental lineage is involved in mouse intestinal regeneration

The paper identifies an Lgr5-independent developmental lineage in mouse intestinal regeneration through single-cell RNA sequencing and lineage tracing experiments.

Duodenal organoids from metabolic dysfunction-associated steatohepatitis patients exhibit altered digestive homeostasis

This study examines duodenal organoids from MASH patients and finds altered digestive homeostasis and junctional protein misexpression without barrier dysfunction.

Lgr5 Controls Extracellular Matrix Production By Stem Cells In The Developing Intestine

This study shows Lgr5 regulates extracellular matrix production in fetal intestinal stem cells, affecting their maturation and niche environment.