Author

Lu Jia

Cold Spring Harbor Laboratory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Adrian R. KraineriD· 1 shared Alexander J. KraliD· 1 shared GeunYoung SimiD· 1 shared Ledong WaniD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 6 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

Adrian R. KrainerORCID

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

Splice-switching ASOs targeting an Alu-derived exon in the AURKA 5'UTR collapse an SRSF1-AURKA-MYC oncogenic circuit in pancreatic cancer

Alexander J. Kral, Lu Jia, GeunYoung Sim, Ledong Wan, Adrian R. Krainer

This study identifies an SRSF1-AURKA-MYC oncogenic circuit in pancreatic cancer and shows that splice-switching ASOs targeting AURKA 5'UTR splicing disrupts this circuit, reducing cell viability and inducing apoptosis.

bioRxiv · Apr 14, 2025 · PreprintCancer Biology