Author

Lucas Lee

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Assay:electrophysiology· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Emily WagneriD· 1 shared Erica MarqueziD· 1 shared Heather L. StruckmaniD· 1 shared Janice M. Amsler· 1 shared Jennifer NA Silva· 1 shared Jonathan D. MorenoiD· 1 shared Jonathan R. SilvaiD· 1 shared Joshua D JosefiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

Emily WagnerORCID

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Author profile →

1 paper

Recent·Most cited

Common Genetic Variants of The Cardiac Sodium Channel Alter Patient Response to Class 1b Antiarrhythmics

Martina Marras, Joshua D Josef, Thomas Schuster, Heather L. Struckman, Emily Wagner, Lucas Lee, Kyle Smith, Janice M. Amsler, Lucy S. Woodbury, Erica Marquez, Nathaniel Huebsch, Jonathan D. Moreno, Jennifer NA Silva, Jonathan R. Silva

The paper shows that a common SCN5A variant, S1103Y, alters mexiletine's pharmacological response in induced pluripotent stem cell-derived cardiomyocytes, leading to proarrhythmic effects.

The Journal of Precision Medicine Health and Disease · Mar 19, 2026Peer-reviewedPhysiology