Elevating levels of neuronal MCU in the hippocampus enhances mitochondrial calcium uptake and respiratory efficiency proportional to demand
Mikel L. Cawley, Ryan N. Montalvo, Mason Wheeler, Lucy L. Turner, Jessica M. Pfleger, Zhen Yan, Shannon Farris
This study shows that increasing neuronal MCU in the hippocampus improves mitochondrial calcium uptake and respiratory efficiency in response to energy demand.
bioRxiv · Apr 16, 2026 · PreprintNeuroscience