Shannon Farris

This study shows that increasing neuronal MCU in the hippocampus improves mitochondrial calcium uptake and respiratory efficiency in response to energy demand.

The paper compares mitochondrial morphology and function in hippocampal CA1 and CA2 circuits, finding cell-type and input-specific differences that may influence circuit properties and disease vulnerability.

The paper uses multiplexed smFISH to analyze the spatial organization of 15 synaptic neuropil localized mRNAs in rodent hippocampus, finding that colocalization patterns scale with mRNA abundance.

This study investigates the input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons using super resolution imaging and knockout-validated antibodies.

This study shows that MCU regulates synaptic plasticity specifically at CA2 distal dendrites by maintaining mitochondrial morphology and distribution, with loss of MCU causing LTP deficits and mitochondrial fragmentation.

The paper shows that mitochondria in CA2 distal dendrites are larger and enriched in MCU, linking synaptic activity to mitochondrial morphology and function.

The paper optimizes protein expansion microscopy (proExM) to better visualize subcellular structures like mitochondria and the Golgi apparatus in mouse brain tissue.

This study investigates the role of CA2 pyramidal neurons in hippocampal oscillations and social behavior using DREADDs in mice, finding bidirectional regulation of low gamma oscillations and impaired social approach with inhibition.