Blood-borne sphingosine 1-phosphate maintains vascular resistance and cardiac function.
Ilaria Del Gaudio, Philippe Bonnin, Emilie Vessières, Estelle Robidel, Manuella Garcia, Coralyne Proux, Alexandre Boutigny, Véronique Baudrie, Hoa Thi Thuy Ha, Ludovic Couty, Nicolò Faedda, Nesrine Mebrek, Théo Morel, Anja Nitzsche, Stéphanie Baron, , Eric Camerer
This study shows that blood-borne sphingosine 1-phosphate (S1P) maintains vascular resistance and cardiac function through albumin-S1P and myocyte S1PR signaling in mice.
bioRxiv · Jan 15, 2025 · PreprintPhysiology