Author

M. A. Care

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

G. M. Doody· 2 shared R. Tooze· 2 shared A. Brodbelt· 1 shared A. Bruning-Richardson· 1 shared A. Chakrabarty· 1 shared A. Droop· 1 shared A. F-Bruns· 1 shared A. Ismail· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersImmunology

G. M. Doody

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Author profile →

4 papers

Recent·Most cited

APRIL drives a co-ordinated but diverse response as a foundation for plasma cell longevity.

M. A. Care, G. M. Doody, S. J. Stephenson, R. M. Tooze

The paper investigates how APRIL signaling promotes plasma cell longevity by activating multiple transcriptional programs in human plasmablasts.

bioRxiv · Jun 15, 2021 · PreprintImmunology

A dichotomy in association of core transcription factors and gene regulation during the activated B-cell to plasmablast transition.

M. Cocco, M. A. Care, M. Al-Maskari, G. M. Doody, R. Tooze

This study identifies a dichotomy in the association of core transcription factors with gene regulation during the activated B-cell to plasmablast transition, showing IRF4 and XBP1 drive ASC gene expression while BLIMP1 represses ABC genes.

bioRxiv · Dec 23, 2019 · PreprintImmunology

JARID2 facilitates transcriptional reprogramming in glioblastoma in response to standard treatment

N. Rippaus, A. F-Bruns, G. Tanner, C. Taylor, A. Droop, A. Bruning-Richardson, M. A. Care, J. Wilkinson, M. D. Jenkinson, A. Brodbelt, A. Chakrabarty, A. Ismail, S. C. Short, L. F. Stead

The paper identifies JARID2-mediated transcriptional reprogramming in glioblastoma post-treatment, showing dysregulated genes with JARID2 binding sites are universally altered in recurrent tumors.

bioRxiv · Jun 17, 2019 · PreprintCancer Biology

Growth-factor like gene regulation is separable from survival and maturation in antibody secreting cells

S. S. Stephenson, M. A. Care, I. Fan, A. Zougman, D. Westhead, G. Doody, R. Tooze

The paper shows that growth factor-like gene regulation in human antibody secreting cells is transient and distinct from survival and maturation processes.

bioRxiv · Oct 11, 2018Immunology