Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
5 papers
Recent·Most cited
H. J. Close, L. F. Stead, J. Nsengimana, K. Reilly, A. Droop, H. Wurdak, R. K. Mathew, R. Corns, J. A. Newton-Bishop, A. A. Melcher, S. C. Short, G. P. Cook, E. B. Wilson
bioRxiv · Oct 4, 2019Immunology
M. Boissinot, H. King, M. Adams, J. Higgins, T. A. Ward, L. P. Steele, D. Tams, R. Morton, E. Polson, B. da Silva, A. P. Droop, J. L. Hayes, H. Martin, P. Laslo, E. E. Morrison, , S. C. Short
This study identifies miR-1300 as a potent cytotoxic microRNA in glioblastoma cells, causing cytokinesis failure and apoptosis, with potential therapeutic applications.
bioRxiv · Oct 1, 2019 · PreprintCancer Biology
N. Rippaus, A. F-Bruns, G. Tanner, C. Taylor, A. Droop, A. Bruning-Richardson, M. A. Care, J. Wilkinson, M. D. Jenkinson, A. Brodbelt, A. Chakrabarty, A. Ismail, S. C. Short, L. F. Stead
The paper identifies JARID2-mediated transcriptional reprogramming in glioblastoma post-treatment, showing dysregulated genes with JARID2 binding sites are universally altered in recurrent tumors.
bioRxiv · Jun 17, 2019 · PreprintCancer Biology
B. da Silva, E. S. Polson, A. Droop, R. K. Mathew, L. F. Stead, J. Williams, S. C. Short, M. Scarcia, G. Mavria, H. Wurdak
The paper shows that ROCKi promotes neurite-like outgrowth in GBM cells, forming radiation-resistant multicellular networks that can be reversed.
bioRxiv · Nov 10, 2018Cancer Biology
E. S. Polson, V. B. Kuchler, C. Abbosh, E. M. Ross, R. K. Mathew, H. A. Beard, E. Chuntharpursat-Bon, J. Williams, B. Da Silva, H. Shao, A. Patel, A. J. Davies, A. Droop, H. B. S. Griffiths, P. Chumas, , H. Wurdak
The paper shows KHS101 inhibits HSPD1 in glioblastoma cells, causing metabolic dysfunction and tumor growth reduction without affecting normal cells.
bioRxiv · Oct 18, 2017Cancer Biology