Author

M. A. Frederick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:trajectory inference· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Approach:deep learning· 1

Frequent Co-Authors

A. J. Getzler· 2 shared C. Toma· 2 shared H. Diao· 2 shared J. J. Milner· 2 shared J. Kim· 2 shared M. E. Pipkin· 2 shared S. Crotty· 2 shared S. M. Tsuda· 2 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

A. J. Getzler

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8+ T stem cell memory

A. J. Getzler, M. A. Frederick, J. J. Milner, T. Venables, H. Diao, C. Toma, S. Nagaraja, D. Albao, S. Belanger, S. M. Tsuda, J. Kim, S. Crotty, A. Goldrath, M. E. Pipkin

This study identifies Mll1 as a key factor in establishing CD8+ T stem cell memory by promoting H3K4me3 deposition and regulating Pol II elongation during TCR stimulation.

bioRxiv · Jan 18, 2023 · PreprintImmunology

Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny

H. Diao, R. Chen, S. M. Tsuda, D. Wang, M. A. Frederick, J. Kim, P. P. Karunadharma, G. J. Martinez, A. J. Getzler, C. Toma, J. J. Milner, T. C. Venables, D. M. Martin, A. W. Goldrath, S. Crotty, M. E. Pipkin

The paper defines single-cell trajectories and identifies chromatin regulators that establish antiviral CD8 T cell heterogeneity during acute and chronic infections.

bioRxiv · Aug 11, 2021 · PreprintImmunology