Author

C. Toma

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:scRNA-seq· 3 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2

Frequent Co-Authors

A. W. Goldrath· 3 shared J. J. Milner· 3 shared A. J. Getzler· 2 shared H. Diao· 2 shared J. Kim· 2 shared J. T. Chang· 2 shared M. A. Frederick· 2 shared M. E. Pipkin· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersImmunology

A. W. Goldrath

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Author profile →

4 papers

Recent·Most cited

Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8+ T stem cell memory

A. J. Getzler, M. A. Frederick, J. J. Milner, T. Venables, H. Diao, C. Toma, S. Nagaraja, D. Albao, S. Belanger, S. M. Tsuda, J. Kim, S. Crotty, A. Goldrath, M. E. Pipkin

This study identifies Mll1 as a key factor in establishing CD8+ T stem cell memory by promoting H3K4me3 deposition and regulating Pol II elongation during TCR stimulation.

bioRxiv · Jan 18, 2023 · PreprintImmunology

Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny

H. Diao, R. Chen, S. M. Tsuda, D. Wang, M. A. Frederick, J. Kim, P. P. Karunadharma, G. J. Martinez, A. J. Getzler, C. Toma, J. J. Milner, T. C. Venables, D. M. Martin, A. W. Goldrath, S. Crotty, M. E. Pipkin

The paper defines single-cell trajectories and identifies chromatin regulators that establish antiviral CD8 T cell heterogeneity during acute and chronic infections.

bioRxiv · Aug 11, 2021 · PreprintImmunology

Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population

J. Milner, H. Nguyen, K. Omilusik, M. Reina-Campos, M. Tsai, C. Toma, A. D. Delpoux, B. Boland, S. M. Hedrick, J. T. Chang, A. W. Goldrath

This study identifies a terminally differentiated effector memory CD8 T cell population with unique molecular and functional properties that challenge classical definitions of effector memory cells.

bioRxiv · Jul 17, 2020Immunology

Functional delineation of tissue-resident CD8 T cell heterogeneity during infection and cancer

J. J. Milner, C. Toma, Z. He, N. S. Kurd, Q. P. Nguyen, B. McDonald, L. Quezada, C. E. Widjaja, D. A. Witherden, J. T. Crowl, G. W. Yeo, J. T. Chang, K. D. Omilusik, A. W. Goldrath

This study identifies distinct CD8+ T cell subsets in non-lymphoid tissues during infection and cancer, revealing their functional roles and regulatory mechanisms.

bioRxiv · Mar 5, 2020 · PreprintImmunology