Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny
H. Diao, R. Chen, S. M. Tsuda, D. Wang, M. A. Frederick, J. Kim, P. P. Karunadharma, G. J. Martinez, A. J. Getzler, C. Toma, J. J. Milner, T. C. Venables, D. M. Martin, A. W. Goldrath, S. Crotty, M. E. Pipkin
The paper defines single-cell trajectories and identifies chromatin regulators that establish antiviral CD8 T cell heterogeneity during acute and chronic infections.
bioRxiv · Aug 11, 2021 · PreprintImmunology