Author

M. E. Pipkin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:statistical model· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:ChIP-seq· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2

Frequent Co-Authors

A. J. Getzler· 2 shared C. Toma· 2 shared G. J. Martinez· 2 shared H. Diao· 2 shared J. J. Milner· 2 shared J. Kim· 2 shared M. A. Frederick· 2 shared S. Crotty· 2 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

A. J. Getzler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Mll1 pioneers histone H3K4me3 deposition and promotes formation of CD8+ T stem cell memory

A. J. Getzler, M. A. Frederick, J. J. Milner, T. Venables, H. Diao, C. Toma, S. Nagaraja, D. Albao, S. Belanger, S. M. Tsuda, J. Kim, S. Crotty, A. Goldrath, M. E. Pipkin

This study identifies Mll1 as a key factor in establishing CD8+ T stem cell memory by promoting H3K4me3 deposition and regulating Pol II elongation during TCR stimulation.

bioRxiv · Jan 18, 2023 · PreprintImmunology

Polycomb Repressive Complex 1 subunit Cbx4 positively regulates effector responses in CD8 T cells

G. A. Melo, T. Xu, C. Caloba, A. W. Schutte, G. Brum, T. O. Passos, L. Higa, A. N. A. Goncalves, A. Tanuri, J. P. B. Viola, M. B. F. Werneck, H. Nakaya, M. E. Pipkin, G. J. Martinez, R. M. Pereira

This study shows that Cbx4 promotes effector CD8 T cell differentiation through SUMOylation and chromodomain mechanisms, impacting memory cell formation during viral infection.

bioRxiv · Oct 3, 2022 · PreprintImmunology

Single-cell lineage trajectories and chromatin regulators that initialize antiviral CD8 T cell ontogeny

H. Diao, R. Chen, S. M. Tsuda, D. Wang, M. A. Frederick, J. Kim, P. P. Karunadharma, G. J. Martinez, A. J. Getzler, C. Toma, J. J. Milner, T. C. Venables, D. M. Martin, A. W. Goldrath, S. Crotty, M. E. Pipkin

The paper defines single-cell trajectories and identifies chromatin regulators that establish antiviral CD8 T cell heterogeneity during acute and chronic infections.

bioRxiv · Aug 11, 2021 · PreprintImmunology

CAR/Nr1i3 directs T cell adaptation to bile acids in the small intestine

M. L. Chen, X. Huang, H. Wang, Y. Liu, J. Shang, A. Eliason, C. Hegner, H. Park, B. Frey, G. Wang, D. J. Kojetin, C. T. Weaver, M. E. Pipkin, D. D. Moore, M. S. Sundrud

This study identifies CAR/Nr1i3 as a regulator of T cell adaptation to bile acids in the small intestine, showing its role in detoxification and inflammation resolution.

bioRxiv · Jul 30, 2020 · PreprintImmunology