Author

M. A. Ruehle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:rat· 1

Frequent Co-Authors

R. E. Guldberg· 3 shared A. Cheng· 1 shared B. Nelson· 1 shared B. S. Klosterhoff· 1 shared E. A. Eastburn· 1 shared J. A. Weiss· 1 shared J. D. Boerckel· 1 shared J. Kaiser· 1 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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3 shared papersBioengineering

R. E. Guldberg

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3 papers

Recent·Most cited

Effects of Controlled Dual Growth Factor Delivery on Bone Regeneration Following Composite Bone-Muscle Injury

R. Subbiah, A. Cheng, M. A. Ruehle, M. H. Hettiaratchi, L. E. Bertassoni, R. E. Guldberg

This study evaluates a smart delivery system for dual growth factor (BMP-2 and VEGF) release in composite bone-muscle injuries, finding no synergistic effect but improved bone healing with low-dose delivery.

bioRxiv · Mar 25, 2020Bioengineering

Mechanical Regulation of Microvascular Angiogenesis

M. A. Ruehle, E. A. Eastburn, S. A. LaBelle, L. Krishnan, J. A. Weiss, J. D. Boerckel, L. B. Wood, R. E. Guldberg, N. J. Willett

This study investigates how mechanical strain on the extracellular matrix affects microvascular angiogenesis, finding that timing and magnitude of compression significantly influence vessel growth and signaling pathways.

bioRxiv · Jan 14, 2020 · PreprintBioengineering

Real-time monitoring of mechanical cues in the regenerative niche reveal dynamic strain magnitudes that enhance bone repair

B. S. Klosterhoff, J. Kaiser, B. Nelson, S. S. Karipott, M. A. Ruehle, S. J. Hollister, J. Weiss, K. G. Ong, N. Willett, R. E. Guldberg

This study uses an implantable strain sensor to monitor mechanical cues during bone repair in rats, showing that dynamic strain magnitudes correlate with healing status.

bioRxiv · Jun 6, 2019 · PreprintBioengineering