Author

L. Krishnan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

R. E. Guldberg· 3 shared N. J. Willett· 2 shared A. E. Qualls· 1 shared A. S. Nichenko· 1 shared A. Yin· 1 shared C. E. Vantucci· 1 shared E. A. Eastburn· 1 shared H. Y. Stevens· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBioengineering

R. E. Guldberg

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3 papers

Recent·Most cited

Mechanical Regulation of Microvascular Angiogenesis

M. A. Ruehle, E. A. Eastburn, S. A. LaBelle, L. Krishnan, J. A. Weiss, J. D. Boerckel, L. B. Wood, R. E. Guldberg, N. J. Willett

This study investigates how mechanical strain on the extracellular matrix affects microvascular angiogenesis, finding that timing and magnitude of compression significantly influence vessel growth and signaling pathways.

bioRxiv · Jan 14, 2020 · PreprintBioengineering

PGC-1α overexpression partially rescues impaired oxidative and contractile pathophysiology following volumetric muscle loss injury

W. M. Southern, A. S. Nichenko, K. F. Tehrani, M. J. McGranahan, L. Krishnan, A. E. Qualls, N. J. Jenkins, L. J. Mortensen, H. Yin, A. Yin, R. E. Guldberg, S. M. Greising, J. A. Call

This study shows that PGC-1α overexpression improves oxidative capacity and muscle strength in VML-injured muscle, suggesting it as a potential therapeutic target.

bioRxiv · Jan 31, 2019Physiology

Effects of BMP-2 dose and delivery of microvascular fragments on healing of bone defects with concomitant volumetric muscle loss

M. Ruehle, L. Krishnan, C. E. Vantucci, Y. Wang, H. Y. Stevens, K. Roy, R. E. Guldberg, N. J. Willett

This study tests the effect of BMP-2 dose and co-delivery of microvascular fragments on healing of bone defects with muscle loss, finding dose-dependent bone regeneration without heterotopic ossification.

bioRxiv · Sep 27, 2018Bioengineering