Author

M. A. Schelling

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Organism:zebrafish· 1

Frequent Co-Authors

D. G. Sashital· 2 shared G. T. Nguyen· 2 shared A. Davis· 1 shared A. Sritharan· 1 shared B. J. Nikolau· 1 shared K. A. Buscher· 1 shared K. Saito· 1 shared L. E. Alexander· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersBiochemistry

D. G. Sashital

Mutual co-authors in cluster

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3 papers

Recent·Most cited

CRISPR-Cas12a exhibits metal-dependent specificity switching

G. T. Nguyen, M. A. Schelling, K. A. Buscher, A. Sritharan, D. G. Sashital

This study shows that Cas12a's specificity changes with Mg2+ concentration, affecting cleavage efficiency and phage escape routes in different cellular environments.

bioRxiv · Nov 29, 2023Biochemistry

CRISPR-Cas effector specificity and target mismatches determine phage escape outcomes

M. A. Schelling, G. T. Nguyen, D. G. Sashital

This study shows that Cas12a mismatch tolerance and pre-existing target mismatches influence phage evolution, with liquid media leading to more phage escape despite in vitro cleavage activity.

bioRxiv · May 30, 2022 · PreprintMicrobiology

Evaluation of the functional role of the maize Glossy2 and Glossy2-like genes in cuticular lipid deposition

L. E. Alexander, Y. Okazaki, M. A. Schelling, A. Davis, X. Zheng, L. Rizhsky, M. Yandeau-Nelson, K. Saito, B. J. Nikolau

Transgenic experiments show Gl2-like and Gl2 genes in maize have overlapping but divergent roles in cuticular lipid deposition, with Gl2-like requiring a catalytic motif for function.

bioRxiv · Feb 27, 2020Biochemistry