Author

M. Badiee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:DNA methylation· 1 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Leung· 2 shared A. Aksimentiev· 1 shared A. K. Leung· 1 shared A. L. Kenet· 1 shared G. Teodoro· 1 shared K. Coshic· 1 shared L. Pollack· 1 shared L. R. Ganser· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiophysics

A. Leung

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Length-dependent Intramolecular Coil-to-Globule Transition in Poly(ADP-ribose) Induced by Cations

T. Wang, K. Coshic, M. Badiee, A. Aksimentiev, L. Pollack, A. Leung

This study investigates how the length of poly(ADP-ribose) (PAR) affects its structural transitions in the presence of Mg2+ ions, revealing length-dependent compaction and bundle formation.

bioRxiv · Oct 25, 2023 · PreprintBiophysics

Switch-like Compaction of Poly(ADP-ribose) Upon Cation Binding

M. Badiee, A. L. Kenet, L. R. Ganser, T. Paul, S. Myong, A. K. Leung

This study shows PAR is stiffer than DNA/RNA and undergoes switch-like compaction in response to cation binding and protein interactions.

bioRxiv · Mar 11, 2023 · PreprintBiophysics

The DarTG toxin-antitoxin system provides phage defense by ADP-ribosylating viral DNA

M. LeRoux, S. Srikant, M. L. Littlehale, G. Teodoro, S. Doron, M. Badiee, A. Leung, R. Sorek, M. T. Laub

This study identifies DarTG toxin-antitoxin systems in E. coli that defend against phage by ADP-ribosylating viral DNA, with phages evolving resistance through DNA polymerase or anti-DarT factors.

bioRxiv · Sep 27, 2021 · PreprintMicrobiology