Author

M. Beato

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cancer Biology· 1 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:chromatin & epigenetic regulation· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1

Frequent Co-Authors

P. Sharma· 3 shared B. Oliva· 2 shared G. Munoz-Gil· 2 shared J. A. Torreno-Pina· 2 shared M. Lewenstein· 2 shared N. Mateos· 2 shared A. Daulny· 1 shared A. Kumar· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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3 shared papersEvolutionary Biology

P. Sharma

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Evolutionary analysis reveals the role of a non-catalytic domain of peptidyl arginine deiminase 2 in transcriptional regulation

J. L. Villanueva-Canas, N. Fernandez-Fuentes, D. Saul, R. L. Kosinsky, C. Teyssier, M. E. Rogalska, F. P. Perez, B. Oliva, C. Notredame, M. Beato, P. Sharma

The paper identifies positively selected residues in the non-catalytic domain of PADI2 and links them to transcriptional regulation and cellular proliferation.

bioRxiv · Sep 19, 2022Evolutionary Biology

Particle flow modulates growth dynamics and nanoscale-arrested growth of transcription factor condensates in living cells

G. Munoz-Gil, C. Romero-Aristizabal, N. Mateos, F. Campelo, L. I. de LLobet-Cucalon, M. Beato, M. Lewenstein, M. Garcia-Parajo, J. A. Torreno-Pina

The paper investigates the biophysical properties of transcription factor condensates using single molecule imaging and modeling, revealing that growth dynamics are regulated by particle flow and molecular escaping.

bioRxiv · Jan 11, 2022 · PreprintBiophysics

Phase separation of tunable biomolecular condensates predicted by an interacting particle model

G. Munoz-Gil, C. Romero, N. Mateos, L. I. de Llobet Cucalon, M. Beato, M. Lewenstein, M. F. Garcia-Parajo, J. A. Torreno-Pina

The paper develops a theoretical model of phase separation using interaction probabilities and validates it with single-molecule experiments on transcription factor condensates.

bioRxiv · Sep 9, 2020 · PreprintBiophysics

Arginine citrullination at the C-terminal domain controls RNA Polymerase transcription

P. Sharma, A. Lioutas, N. F. Fuentes, J. Quilez, J. C. Caballero, R. H. G. Wright, C. Di Vona, F. Le Dily, R. Schuller, D. Eick, B. Oliva, M. Beato

The paper identifies citrullination of arginine1810 on RNAP2-CTD by PADI2 as a regulator of transcription and cell proliferation in breast cancer.

bioRxiv · May 10, 2018Cancer Biology

Cell-specific modulation of nuclear pore complexes controls cell cycle entry during asymmetric division

A. Kumar, P. Sharma, Z. Shcheprova, A. Daulny, T. Sanmartin, I. Matucci, C. Funaya, M. Beato, M. Mendoza

The paper identifies a mechanism where Hos3-mediated NPC deacetylation in budding yeast daughter cells delays cell cycle entry by regulating transcriptional repression and gene silencing.

bioRxiv · Oct 14, 2017Cell Biology