Author

M. Blume

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

D. Maus· 2 shared E. Rajendran· 2 shared F. Seeber· 2 shared K. Kirk· 2 shared M. J. McConville· 2 shared S. Broer· 2 shared S. J. Fairweather· 2 shared T. Hoffmann· 2 shared

Activity by Year

2018-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

D. Maus

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Author profile →

4 papers

Recent·Most cited

Screening the MMV Pathogen Box reveals the mitochondrial bc1-complex as a drug target in mature Toxoplasma gondii bradyzoites.

D. Maus, E. Putrianti, T. Hoffmann, M. Laue, F. Seeber, M. Blume

The paper screens the MMV Pathogen Box to identify compounds active against Toxoplasma gondii bradyzoites and finds the mitochondrial bc1-complex as a drug target.

bioRxiv · Nov 23, 2023 · PreprintMicrobiology

Coordinated Action of Multiple Transporters in the Acquisition of Essential Cationic Amino Acids by the Intracellular Parasite Toxoplasma gondii

S. J. Fairweather, E. Rajendran, M. Blume, K. Javed, B. Steinhoefel, M. J. McConville, K. Kirk, S. Broer, G. G. van Dooren

This study identifies TgApiAT6-1 as a second arginine transporter in Toxoplasma gondii, showing it mediates both lysine and arginine uptake and is essential for parasite proliferation.

bioRxiv · Jun 25, 2021Microbiology

In vitro maturation of Toxoplasma gondii bradyzoites in human myotubes and their metabolomic characterization

C. Christiansen, D. Maus, E. Hoppenz, F. Melerowicz, J. Scholz, M. Murillo-Leon, T. Steinfeldt, T. Hoffmann, F. Seeber, M. Blume

This study develops an in vitro model of mature Toxoplasma gondii bradyzoite cysts in human myotubes and characterizes their metabolomic profile.

bioRxiv · Jan 15, 2021Microbiology

Characterization of the apicomplexan amino acid transporter (ApiAT) family in Toxoplasma gondii

K. E. R. Parker, S. J. Fairweather, E. Rajendran, M. Blume, M. J. McConville, S. Broer, K. Kirk, G. van Dooren

The paper identifies and characterizes the ApiAT family of amino acid transporters in Toxoplasma gondii, showing their role in amino acid scavenging and parasite virulence.

bioRxiv · Apr 26, 2018Microbiology