Author

E. Rajendran

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 7

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell type annotation· 4 Assay:proteomics· 4 Organism:human· 3 Organism:Drosophila· 2 Research Focus:host-pathogen & immune response· 2 Approach:biophysical modeling· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

G. G. van Dooren· 4 shared G. van Dooren· 3 shared K. Kirk· 3 shared B. Steinhoefel· 2 shared E. T. Tjhin· 2 shared J. A. Hayward· 2 shared M. Blume· 2 shared M. J. McConville· 2 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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4 shared papersMicrobiology

G. G. van Dooren

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7 papers

Recent·Most cited

A screen of drug-like molecules identifies chemically diverse electron transport chain inhibitors in apicomplexan parasites

J. A. Hayward, F. V. Makota, D. Cihalova, E. Rajendran, S. M. Zwahlen, L. Shuttleworth, U. Wiedemann, C. Spry, K. J. Saliba, A. G. Maier, G. G. van Dooren

The paper screens drug-like molecules to identify new electron transport chain inhibitors in apicomplexan parasites, finding chemically diverse compounds effective against resistant strains.

bioRxiv · Feb 13, 2022Microbiology

Coordinated Action of Multiple Transporters in the Acquisition of Essential Cationic Amino Acids by the Intracellular Parasite Toxoplasma gondii

S. J. Fairweather, E. Rajendran, M. Blume, K. Javed, B. Steinhoefel, M. J. McConville, K. Kirk, S. Broer, G. G. van Dooren

This study identifies TgApiAT6-1 as a second arginine transporter in Toxoplasma gondii, showing it mediates both lysine and arginine uptake and is essential for parasite proliferation.

bioRxiv · Jun 25, 2021Microbiology

Divergent features of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii parasites

J. A. Hayward, E. Rajendran, S. M. Zwahlen, P. Faou, G. G. van Dooren

This study identifies novel and divergent components of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii, revealing differences from mammalian Complex III.

bioRxiv · Aug 18, 2020Microbiology

Substrate-mediated regulation of the arginine transporter of Toxoplasma gondii

E. Rajendran, M. Clark, C. Goulart, B. Steinhoefel, E. T. Tjhin, N. C. Smith, K. Kirk, G. G. van Dooren

This study shows that Toxoplasma gondii regulates its arginine transporter TgApiAT1 expression in response to arginine availability, mediated by a uORF in the transcript.

bioRxiv · Oct 9, 2019Microbiology

Identification of cryptic stator subunits from an apicomplexan ATP synthase

D. Huet, E. Rajendran, G. van Dooren, S. Lourido

The paper identifies 11 novel subunits of the Toxoplasma ATP synthase, including ICAP2 and ICAP18, which show distant homology to mammalian stator subunits and are essential for complex function.

bioRxiv · May 11, 2018Microbiology

Identification of a divergent cytochrome c oxidase complex in the mitochondrial proteome of Toxoplasma gondii

A. Seidi, L. S. Muellner-Wong, E. Rajendran, E. T. Tjhin, L. Dagley, V. Y. T. Aw, A. Webb, C. J. Tonkin, G. van Dooren

The paper identifies a divergent cytochrome c oxidase complex in Toxoplasma gondii mitochondria, revealing unique proteins essential for parasite survival.

bioRxiv · May 11, 2018Microbiology

Characterization of the apicomplexan amino acid transporter (ApiAT) family in Toxoplasma gondii

K. E. R. Parker, S. J. Fairweather, E. Rajendran, M. Blume, M. J. McConville, S. Broer, K. Kirk, G. van Dooren

The paper identifies and characterizes the ApiAT family of amino acid transporters in Toxoplasma gondii, showing their role in amino acid scavenging and parasite virulence.

bioRxiv · Apr 26, 2018Microbiology