Author

M. Borghesan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

A. O'Loghlen· 2 shared P. Carpintero-Fernandez· 2 shared H. Peinado· 1 shared J. A. Fafian-Labora· 1 shared J. Fafian-Labora· 1 shared J. Munoz· 1 shared M. Mayan· 1 shared O. Eleftheriadou· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersCancer Biology

A. O'Loghlen

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2 papers

Recent·Most cited

The coagulation factor IX (F9) loss of function prevents the cell cycle arrest induced by CDK4/6 inhibitors treatment

P. Carpintero-Fernandez, M. Borghesan, O. Eleftheriadou, J. Fafian-Labora, T. Mitchell, T. D. Nightingale, M. Mayan, A. O'Loghlen

This study identifies F9 as a gene that facilitates cell cycle arrest induced by CDK4/6 inhibitors in breast cancer cells, suggesting its role in senescence and potential therapeutic implications.

bioRxiv · Nov 30, 2021Cancer Biology

Exosomes are key regulators of non-cell autonomous communication in senescence

M. Borghesan, J. A. Fafian-Labora, P. Carpintero-Fernandez, P. Ximenez- Embun, H. Peinado, J. Munoz, A. O'Loghlen

This study identifies exosomes as key mediators of non-cell autonomous senescence by transmitting the senescent phenotype through a non-canonical interferon pathway.

bioRxiv · Jun 27, 2018Cell Biology