The coagulation factor IX (F9) loss of function prevents the cell cycle arrest induced by CDK4/6 inhibitors treatment
P. Carpintero-Fernandez, M. Borghesan, O. Eleftheriadou, J. Fafian-Labora, T. Mitchell, T. D. Nightingale, M. Mayan, A. O'Loghlen
This study identifies F9 as a gene that facilitates cell cycle arrest induced by CDK4/6 inhibitors in breast cancer cells, suggesting its role in senescence and potential therapeutic implications.
bioRxiv · Nov 30, 2021Cancer Biology