Author

M. Brizuela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:behavioral assay· 1 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. Julius· 2 shared K. K. Touhara· 2 shared N. D. Rossen· 2 shared S. M. Brierley· 2 shared A. Hendry· 1 shared A. M. Harrington· 1 shared A. Venkataramen· 1 shared C. Bueno Silva· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersPhysiology

D. Julius

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Author profile →

2 papers

Recent·Most cited

Crypt and Villus Enterochromaffin Cells are Distinct Stress Sensors in the Gut

K. K. Touhara, N. D. Rossen, F. Deng, T. Chu, A. M. Harrington, S. Garcia Caraballo, M. Brizuela, T. O'Donnell, O. Cil, S. M. Brierley, Y. Li, D. Julius

This study identifies distinct roles for crypt and villus enterochromaffin cells in sensing gut irritants and oxidative stress through different TRP channels and signaling mechanisms.

bioRxiv · Feb 6, 2024Physiology

Gut Enterochromaffin Cells are Critical Drivers of Visceral Pain and Anxiety

J. R. Bayrer, J. Castro, A. Venkataramen, K. K. Touhara, N. D. Rossen, R. D. Morrie, A. Hendry, J. Madden, K. Braverman, G. Schober, M. Brizuela, C. Bueno Silva, H. A. Ingraham, S. M. Brierley, D. Julius

This study shows that enterochromaffin cells drive visceral pain and anxiety through serotonin signaling, with sex differences in baseline sensitivity.

bioRxiv · Apr 4, 2022 · PreprintPhysiology