Gut Enterochromaffin Cells are Critical Drivers of Visceral Pain and Anxiety
J. R. Bayrer, J. Castro, A. Venkataramen, K. K. Touhara, N. D. Rossen, R. D. Morrie, A. Hendry, J. Madden, K. Braverman, G. Schober, M. Brizuela, C. Bueno Silva, H. A. Ingraham, S. M. Brierley, D. Julius
This study shows that enterochromaffin cells drive visceral pain and anxiety through serotonin signaling, with sex differences in baseline sensitivity.
bioRxiv · Apr 4, 2022 · PreprintPhysiology