Author

M. Broussalian

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Organism:human· 1

Frequent Co-Authors

A. C. Foulger· 1 shared A. Rane· 1 shared A. Singh· 1 shared C. Arputhasamy· 1 shared C. Kumsta· 1 shared C. M. Lange· 1 shared E. Battistoni· 1 shared E. H. Choy· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. C. Foulger

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2 papers

Recent·Most cited

Inhibition of early-acting autophagy genes in C. elegans neurons improves protein homeostasis, promotes exopher production, and extends lifespan via the ATG-16.2 WD40 domain

Y. Yang, M. L. Arnold, E. H. Choy, C. M. Lange, K. Poon, M. Broussalian, L.-H. Sun, T. M. Moreno, A. Singh, M. Driscoll, C. Kumsta, M. Hansen

The paper inhibits early-acting autophagy genes in C. elegans neurons, finding that it reduces protein aggregates, increases exopher production, and extends lifespan, with ATG-16.2's WD40 domain being critical for these effects.

bioRxiv · Dec 12, 2022 · PreprintCell Biology

Potassium-chelating drug sodium polystyrene sulfonate enhances lysosomal function and suppresses proteotoxicity

C. Arputhasamy, M. Lucanic, A. Rane, M. Schmidt, T. Garett, A. C. Foulger, M. Broussalian, E. Battistoni, R. B. Brem, G. J. Lithgow, M. Chamoli, J. K. Andersen

This study shows that the FDA-approved drug sodium polystyrene sulfonate enhances lysosomal function and reduces proteotoxicity in C. elegans and human neuronal cells, while also increasing lifespan.

bioRxiv · Oct 21, 2021Cell Biology