Author

M. C. Verhaar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1 Assay:metabolomics· 1

Frequent Co-Authors

C. Cheng· 2 shared C. G. M. van Dijk· 2 shared E. M. Meijer· 2 shared I. Chrifi· 2 shared M. Altelaar· 2 shared R. Maringanti· 2 shared R. Masereeuw· 2 shared A. I. Smits· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersCell Biology

C. Cheng

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Effect of Mechanical Stimuli on the Phenotypic Plasticity of Induced Pluripotent Stem Cell-Derived Vascular Smooth Muscle Cells in a 3D Hydrogel

E. M. Meijer, R. Giles, C. G. M. van Dijk, R. Maringanti, T. B. Wissing, Y. Appels, I. Chrifi, H. Crielaard, M. C. Verhaar, A. I. Smits, C. Cheng

This study examines how mechanical stimuli affect the phenotypic plasticity of hiPSC-derived vascular smooth muscle cells in 3D hydrogels, showing they adapt similarly to primary cells.

bioRxiv · Sep 11, 2023Cell Biology

A complex three-dimensional microfluidic model that mimics the early stage events in the human atherosclerotic artery

R. Maringanti, C. G. M. van Dijk, E. M. Meijer, M. M. Brandt, M. M. Krebber, I. Chrifi, D. J. Duncker, M. C. Verhaar, C. Cheng

This paper develops a 3D microfluidic model of early human atherosclerosis with co-cultured cells and flow to study immune cell recruitment and disease mechanisms.

bioRxiv · Feb 2, 2023 · PreprintCell Biology

Differentiated kidney tubular cell-derived extracellular vesicles enhance maturation of tubuloids

R. S. Lindoso, F. A. Y. Yengej, F. Voellmy, M. Altelaar, E. M. Juncosa, T. Tsikari, C. M. E. Ammerlaan, B. W. M. Van Balkom, M. C. Verhaar, R. Masereeuw

This study shows that extracellular vesicles from kidney tubular cells enhance tubuloid maturation by increasing transport protein expression and triggering key biological pathways.

bioRxiv · Feb 8, 2022Cell Biology

Cysteamine-bicalutamide combination treatment restores alpha-ketoglutarate and corrects proximal tubule phenotype in cystinosis

A. Jamalpoor, C. A. van Gelder, F. A. Yousef Yengej, E. A. Zaal, S. P. Berlingerio, K. R. Veys, C. Pou Casellas, K. Voskuil, K. Essa, C. M. Ammerlaan, L. R. Rega, R. E. N. van der Welle, M. R. Lilien, M. B. Rookmaaker, H. Clevers, , M. J. Janssen

This study identifies alpha-ketoglutarate as a key metabolite in cystinosis and shows that combining cysteamine with bicalutamide corrects proximal tubule defects in cell models and zebrafish.

bioRxiv · Feb 10, 2020 · PreprintPharmacology & Toxicology