M. Capitanio

Optimization of highly inclined Illumination for diffraction-limited and super-resolution microscopy

This paper optimizes the illumination beam in HILO microscopy to improve image quality in both diffraction-limited and super-resolution imaging.

Particle localization using local gradients and its application to nanometer stabilization of a microscope

This paper introduces a method for three-dimensional particle localization using local gradients, achieving nanometer accuracy and sub-ms calculation time, and applies it to stabilize microscopes for sensitive measurements.

Probing mechanotransduction in living cells by optical tweezers and FRET-based molecular force microscopy

The paper introduces a method combining optical tweezers and FRET-based force sensors to study mechanotransduction in living cells.

α-catenin switches between a slip and an asymmetric catch bond with F-actin to cooperatively regulate cell junction fluidity

This study shows that -catenin forms different types of bonds with F-actin depending on its dimerization state and applied force, affecting cell junction fluidity.

Single molecule mechanics resolves the earliest events in force generation by cardiac myosin

This study uses ultra-high-speed optical traps to observe rapid mechanical events in cardiac myosin, showing the working stroke occurs before phosphate release and is influenced by force.