Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells using a diphtheria toxin-based fusion protein
S. Parveen, S. Lun, M. E. Urbanowski, M. Cardin, J. R. Murphy, W. R. Bishai
This study shows that depleting myeloid-derived suppressor cells (MDSCs) using a diphtheria toxin-based fusion protein reduces Mycobacterium tuberculosis burden in mice.
bioRxiv · Dec 10, 2020Microbiology