Author

M. E. Urbanowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Upton· 1 shared D. S. Mortensen· 1 shared E. Nuermberger· 1 shared J. R. Murphy· 1 shared M. Cardin· 1 shared N. Fotouhi· 1 shared N. Hawryluk· 1 shared P. J. Converse· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperPathology

A. Upton

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2 papers

Recent·Most cited

Dual mTORC1/mTORC2 inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis

R. Tasneen, D. S. Mortensen, P. J. Converse, M. E. Urbanowski, A. Upton, N. Fotouhi, E. Nuermberger, N. Hawryluk

This study compares the efficacy of mTOR inhibitors in tuberculosis treatment, finding that CC214-2 reduces relapses more than rapamycin in mouse models.

bioRxiv · Feb 10, 2021Pathology

Effective host-directed therapy for tuberculosis by targeted depletion of myeloid-derived suppressor cells using a diphtheria toxin-based fusion protein

S. Parveen, S. Lun, M. E. Urbanowski, M. Cardin, J. R. Murphy, W. R. Bishai

This study shows that depleting myeloid-derived suppressor cells (MDSCs) using a diphtheria toxin-based fusion protein reduces Mycobacterium tuberculosis burden in mice.

bioRxiv · Dec 10, 2020Microbiology