Author

M. Cisneros-Aguirre

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:human· 1 Assay:structural biology· 1

Frequent Co-Authors

J. M. STARK· 2 shared A. Bonucci· 1 shared A. K. Aggarwal· 1 shared A. Patwardhan· 1 shared A. T. Moreno· 1 shared B. Chen· 1 shared C. A. Birch· 1 shared D. Nicholas· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersBiophysics

J. M. STARK

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Author profile →

3 papers

Recent·Most cited

Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro

D.-D. Vu, A. Bonucci, M. Breniere, M. Cisneros-Aguirre, P. Pelupessy, Z. Wang, L. Carlier, G. Bouvignies, P. Cortes, A. K. Aggarwal, M. Blackledge, Z. Gueroui, V. Belle, J. M. STARK, M. M. Modesti, F. Ferrage

This study characterizes the multivalent interactions of XRCC4 and XLF CTRs, showing they form condensates that enhance DNA ligation in vitro and suggest roles in NHEJ dynamics and cancer biology.

bioRxiv · Jul 12, 2023Biophysics

aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis

O. Molinar-Inglis, C. A. Birch, D. Nicholas, M. Cisneros-Aguirre, A. Patwardhan, B. Chen, N. J. Grimsey, P. K. Gomez-Menzies, H. Lin, L. J. Coronel, M. A. Lawson, H. H. Patel, J. Trejo

This study identifies a novel β-arrestin-2-mediated signaling pathway that mediates aPC/PAR1's anti-apoptotic effects in endothelial cells.

bioRxiv · Mar 27, 2021Cell Biology

XLF acts as a flexible connector during non-homologous end joining

S. M. Carney, A. T. Moreno, S. C. Piatt, M. Cisneros-Aguirre, F. W. Lopezcolorado, J. M. Stark, J. J. Loparo

This study shows that the C-terminal tail of XLF is essential for DNA end alignment during NHEJ, with a minimal length required for efficient end joining.

bioRxiv · Jul 29, 2020Biochemistry