Author

M. A. Lawson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3 Immunology· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 6 Organism:human· 4 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Assay:metagenomics· 3 Assay:metabolomics· 2 Organism:mouse· 2 Approach:biophysical modeling· 1

Frequent Co-Authors

L. J. Hall· 3 shared I. J. O'Neill· 2 shared M. Kujawska· 2 shared A. Gartland· 1 shared A. J. Macpherson· 1 shared A. Jordan· 1 shared A. M. Gontarczyk· 1 shared A. M. Sackheim· 1 shared

Activity by Year

2017-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

L. J. Hall

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

A novel bacteriocin produced by Bifidobacterium longum subsp. infantis has dual antimicrobial and immunomodulatory activity

S. G. Javvadi, M. Kujawska, D. Papp, A. M. Gontarczyk, A. Jordan, M. A. Lawson, I. J. O'Neill, C. Alcon-Giner, R. Kiu, P. Clarke, N. Beraza, L. J. Hall

bioRxiv · Jan 27, 2022 · PreprintMicrobiology

The polyanionic drug suramin neutralizes histones and prevents endotheliopathy

N. Villalba, A. M. Sackheim, M. A. Lawson, L. Haines, Y. L. Chen, S. K. Sonkusare, Y.-T. Ma, J. Li, D. Majumdar, B. A. Bouchard, J. E. Boyson, M. E. Poynter, M. T. Nelson, K. Freeman

This paper shows suramin neutralizes histones, preventing endothelial damage and improving vascular function in inflammatory conditions.

bioRxiv · Dec 9, 2021Immunology

The P2RX7B splice variant modulates osteosarcoma cell behaviour and metastatic properties

L. Tattersall, K. M. Shah, D. L. Lath, A. Singh, J. M. Down, E. De Marchi, A. Williamson, F. Di Virgilio, D. Heymann, E. Adinolfi, W. D. Fraser, D. Green, M. A. Lawson, A. Gartland

This paper shows that the P2RX7B splice variant promotes osteosarcoma metastasis and identifies a novel gene axis inhibited by P2RX7 antagonists.

bioRxiv · May 7, 2021Cancer Biology

aPC/PAR1 confers endothelial anti-apoptotic activity via a discrete β-arrestin-2 mediated SphK1-S1PR1-Akt signaling axis

O. Molinar-Inglis, C. A. Birch, D. Nicholas, M. Cisneros-Aguirre, A. Patwardhan, B. Chen, N. J. Grimsey, P. K. Gomez-Menzies, H. Lin, L. J. Coronel, M. A. Lawson, H. H. Patel, J. Trejo

This study identifies a novel β-arrestin-2-mediated signaling pathway that mediates aPC/PAR1's anti-apoptotic effects in endothelial cells.

bioRxiv · Mar 27, 2021Cell Biology

Bifidobacterium breve UCC2003 exopolysaccharide modulates the early life microbiota by acting as a dietary substrate

D. Puengel, A. Treveil, M. J. Dalby, S. Caim, I. J. Colquhoun, C. Booth, J. Ketskemety, T. Korcsmaros, D. van Sinderen, M. A. Lawson, L. J. Hall

This study shows that Bifidobacterium breve UCC2003 exopolysaccharide (EPS) alters infant microbiota and metabolite profiles by serving as a nutrient substrate.

Nutrients · Mar 29, 2020Peer-reviewedMicrobiology

Infant diet promotes Bifidobacterium community cooperation within a single ecosystem

M. A. Lawson, I. J. O'Neill, M. Kujawska, A. Wijeyesekera, Z. Flegg, L. Chalklen, L. J. Hall

The paper investigates how infant diet influences bifidobacterial community composition and cooperation in the gut, showing resource sharing enhances nutrient utilization and supports Bifidobacterium dominance.

bioRxiv · Jul 23, 2019Microbiology

Antibodies set boundaries limiting microbial metabolite penetration and the resultant mammalian host response

Y. Uchimura, T. Fuhrer, H. Li, M. A. Lawson, M. Zimmermann, M. Gomez de Aguero, B. Yilmaz, F. Ronchi, M. Sorribas, S. Hapfelmeier, S. C. Ganal-Vonarburg, K. D. McCoy, U. Sauer, A. J. Macpherson

The paper develops a model to distinguish microbial and host metabolites using stable isotope tracing and shows that antibodies limit microbial metabolite penetration into host tissues.

bioRxiv · Sep 25, 2017Immunology