Author

J. M. Stark

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Biochemistry· 1 Biophysics· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:chromatin & epigenetic regulation· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

J. M. Coquet· 3 shared J. Ma· 3 shared C. A. Tibbitt· 2 shared C. H. Classon· 2 shared F. W. Lopezcolorado· 2 shared M. Cisneros-Aguirre· 2 shared M. Li· 2 shared S. Nylen· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersImmunology

J. M. Coquet

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Author profile →

7 papers

Recent·Most cited

RAD52 and ERCC6L/PICH have a compensatory relationship for genome stability in mitosis.

B. A. Osia, A. Merkell, F. W. Lopezcolorado, X. Ping, J. M. STARK

This study identifies a compensatory relationship between RAD52 and ERCC6L/PICH in maintaining genome stability during mitosis through CRISPR screens and functional assays.

bioRxiv · Aug 23, 2023Cell Biology

Multivalent interactions of the disordered regions of XLF and XRCC4 foster robust cellular NHEJ and drive the formation of ligation-boosting condensates in vitro

D.-D. Vu, A. Bonucci, M. Breniere, M. Cisneros-Aguirre, P. Pelupessy, Z. Wang, L. Carlier, G. Bouvignies, P. Cortes, A. K. Aggarwal, M. Blackledge, Z. Gueroui, V. Belle, J. M. STARK, M. M. Modesti, F. Ferrage

This study characterizes the multivalent interactions of XRCC4 and XLF CTRs, showing they form condensates that enhance DNA ligation in vitro and suggest roles in NHEJ dynamics and cancer biology.

bioRxiv · Jul 12, 2023Biophysics

Arginine shortage induces replication stress and confers genotoxic resistance by inhibiting histone H4 translation and promoting PCNA polyubiquitination

Y.-C. Wang, A. A. Kelso, A. Karamafrooz, Y.-H. Chen, W.-K. Chen, C.-T. Cheng, Y. Qi, L. Gu, L. Malkas, H.-J. Kung, G.-L. Moldovan, A. Ciccia, J. M. Stark, D. K. Ann

bioRxiv · Jan 31, 2023 · PreprintCancer Biology

Intestinal helminth infection transforms the CD4+ T cell composition of the skin

C. H. Classon, M. Li, J. Ma, A. Lerma Clavero, X. Feng, C. A. Tibbitt, J. M. Stark, R. F. Cardoso, E. Ringqvist, L. Boon, E. Villablanca, A. G. Rothfuchs, L. Eidsmo, J. M. Coquet, S. Nylen

This study shows that intestinal helminth infection alters CD4+ T cell composition in the skin, leading to long-term changes in immune responses to antigens.

bioRxiv · Apr 18, 2021Immunology

Laboratory mice with a wild microbiota generate strong allergic immune responses

J. Ma, C. H. Classon, J. M. Stark, M. Li, H.-J. Huang, S. Vrtala, S. P. Rosshart, S. Nylen, J. M. Coquet

The paper shows that mice with a diverse wild microbiota develop stronger allergic inflammation compared to those without microbial exposure.

bioRxiv · Mar 28, 2021Immunology

Sublingual allergen immunotherapy with recombinant dog allergens prevents airway hyperresponsiveness in a model of asthma marked by vigorous TH2 and TH17 cell responses

J. M. Stark, J. Liu, C. A. Tibbitt, M. Christian, J. Ma, A. Wintersand, B. Murrell, M. Adner, H. Gronlund, G. Gafvelin, J. M. Coquet

This study shows that sublingual immunotherapy with recombinant dog allergens reduces airway hyperresponsiveness and type 2 inflammation in a mouse model of dog allergy.

bioRxiv · Feb 4, 2021Immunology

XLF acts as a flexible connector during non-homologous end joining

S. M. Carney, A. T. Moreno, S. C. Piatt, M. Cisneros-Aguirre, F. W. Lopezcolorado, J. M. Stark, J. J. Loparo

This study shows that the C-terminal tail of XLF is essential for DNA end alignment during NHEJ, with a minimal length required for efficient end joining.

bioRxiv · Jul 29, 2020Biochemistry